I can only assume there must have been some discussion on CN or some YouTube video covering this within the last 15 minutes as we just received 2 requests for this within about 5 minutes of each other 
I’ll have to do some research on how ROI is implemented in that camera. Is this purely a subframe or is it some other capability of the camera that would have to be exposed through the ASCOM driver? if it’s a subframe then how would this differ from just capturing full frame and then cropping the data?
Jared